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KMID : 0382619820020010145
Hanyang Journal of Medicine
1982 Volume.2 No. 1 p.145 ~ p.149
Hemagglutination Inhibition (H-I) Antibodies Against Rubella Virus in Normal Korean Females, 1980
Kim Kyu-Youp

Lee Heung-Jae
Lee Keun Soo
Abstract
Because the rubella is usually an uncomplicated self-limiting disease, it is often ignored by physician. However viral replication in lymphnodes results in viremia, which may cross the placenta and infect the fetus in pregnant female, giving rise to the fetus with congenital rubella syndrome. In order to prevent congenital rubella syndrome, the attenuated virus vaccine have -been developed and widely used. Today, the routine veccination of rubella has beco.me a subject of dispute among physicians in Korea. To get the exact data for rubella antibodies among Korean female, the author has -made a survey for positive rate of H-I antibodies against Rubella.

The results were follows:
1. Rubella antibody positive rate of below 2 years of age and 3 years were 30. 0%, 40.0 % respectively and that of 11 years and 12 years were 70.0 %, 66.6 % respectively.¢¥
2. There was a tendency to show proportionaly increasing positive rate in accordance with the increasing age until 7 years.
3. However the positive rate among 8 years to 12 years groups showed no definite increasing tendency with the increasing age.
4. Over all positive rate of 107 girls were 50.5 %.
5. Judging from above data, the positive rate of child bearing age group might not be more than 70.0 % in Korea.
6. The author could propose the rubella vaccination should be included in the routine vaccination schedule for Korean children.
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